Test Preparation : No special preparation required

Sample : Paraffin Blocks/Tissue in buffered formalin

Methodlogy : IHC

Description :

WHAT IS IT?

IHC CD117 is an immunohistochemistry (IHC) staining method that looks for the CD117 protein in tissue samples using a CD117 antibody. Transmembrane receptor protein CD117, also known as c-kit or stem cell factor receptor (SCFR), is essential for cell proliferation, differentiation, and survival. By staining tissue sections with the CD117 antibody, which binds to the protein if it is present in the sample, the IHC CD117 test identifies and visualises cells that express the CD117 protein inside tissues. The antibody is often attached to a label that can be seen under a microscope to enable the visualization of the associated antibody-antigen complexes. The IHC CD117 test has clinical and academic uses in pathology, stem cell research, cancer diagnosis, and targeted therapeutics. The identification and classification of tissue samples based on CD117 expression can help with the diagnosis of some malignancies, the choice of the best treatment options, and the detection of CD117 expression in tissue samples. When it comes to GISTs, CD117 expression can affect how tyrosine kinase inhibitors are used as a kind of treatment.

HOW DOES IHC CD117 HELPS?

If the criteria given are found for Unisex gender and for all age groups, the result for CD 117 is often positive. The results will confirm the presence of a gastrointestinal stromal tumour and will be helpful both during and following therapy. Results from CD117 tests can help with mast cell tumour diagnosis and help distinguish between seminomas and embryonal carcinomas.

PRECAUTIONS

Make sure you dress in a short-sleeved shirt or one with easily-rollable sleeves. For the allergy panel test, no extra preparation is required. You don't need to change your diet. Normal eating and drinking are permitted. However, your doctor could insist that you abstain from food and drink for a set period of time prior to the test. If extra testing will be conducted on the blood sample, this is done. Depending on your sensitivities, your doctor will offer you particular recommendations.