Test Preparation : No special preparation required

Sample : Paraffin Blocks/Tissue in buffered formalin

Methodlogy : IHC

Description :

WHAT IS IT?

The Cytokeratin 20 (CK-20) Immunohistochemistry (IHC) test is a diagnostic tool used in pathology to detect and describe particular cells inside tissue samples. CK-20 is a cytokeratin subtype found in epithelial cells that is expressed in a variety of organs, most notably the gastrointestinal and urogenital tracts. The IHC-CK-20 test employs antibodies to stain tissue sections, allowing pathologists to detect and study the distribution of CK-20-positive cells. This test is extremely beneficial in the diagnosis of tumors such as colorectal and urothelial carcinomas, as it helps guide treatment methods and improve patient outcomes, particularly in oncology.

WHY?

The Cytokeratin 20 (CK-20) Immunohistochemistry (IHC) test is a critical diagnostic technique for determining tissue composition, particularly in cancer detection. It entails staining tissue slices with antibodies that specifically target CK-20. This enables pathologists to detect and examine the distribution of CK-20-positive cells, giving critical information about the tissue's properties. The CK-20 test is very beneficial in identifying colorectal and urothelial carcinomas, as CK-20 expression patterns reveal tumor cell origin and characteristics. By focusing on the peculiarities of the cancer, healthcare providers may make more accurate diagnoses, establish specific treatment methods, and enhance patient outcomes. Overall, the IHC-CK-20 test is critical for directing treatment decisions, boosting diagnostic accuracy, and improving cancer care.

PRECAUTIONS 

Immunohistochemistry (IHC) Cytokeratin 20 (CK-20) test preparation is critical for accurate and consistent findings. To guarantee appropriate interpretation of test findings, patients should reveal any medical history, current medicines, or existing health issues. While there are no food or activity limits, patients should dress comfortably and notify laboratory workers of any bleeding problems or blood-thinning drugs. Patients should also follow any special directions given by their healthcare practitioner or laboratory, such as ceasing certain drugs or following to fasting restrictions. This proactive approach improves the dependability of test results, allowing for more accurate diagnosis and the creation of treatment methods tailored to the patient's individual condition.