Test Preparation : No special preparation required
Sample : Paraffin Blocks/Tissue in buffered formalin
Methodlogy : IHC
Description :
WHAT IS IT?
Epithelial membrane antigen may be detected and localized in tissue samples using the Immunohistochemistry (IHC) Epithelial Membrane Antigen (EMA) test, a diagnostic method used in pathology. A glycoprotein called epithelial membrane antigen is frequently present on the cell surfaces of epithelial cells, a kind of tissue that borders different bodily structures and cavities. In order to view the antigen under a microscope, the IHC EMA test requires staining tissue slices with certain antibodies that bind to the antigen. Given that the presence of EMA might reveal the epithelial origin of cells, this test is very useful for differentiating between various tumor and tissue types. It helps pathologists identify a number of ailments, including malignancies like adenocarcinomas and certain varieties of mesotheliomas. The IHC EMA test allows medical practitioners to acquire crucial data regarding the cellular make-up and origin of the tissue, which helps them make accurate diagnoses and educated treatment choices for patients.
WHY?
The Epithelial Membrane Antigen (EMA) test used in immunohistochemistry (IHC) is a crucial instrument for making a variety of medical diagnoses. It makes use of certain antibodies to detect the presence of epithelial membrane antigen in tissue samples, giving pathologists a better chance to pinpoint the origins of individual cells. The epithelial character of epithelial tissues is shown by the presence of EMA on their cell surfaces, which is particularly helpful in differentiating between various tumor types. The test's findings aid in more accurate diagnosis and direct suitable treatment plans, including choices on cancer therapy and patient outcomes. Healthcare providers may make educated judgments and customize treatment regimens to each patient's unique requirements by using the IHC EMA test's insights regarding the cellular makeup of tissues. Overall, by ensuring that medical therapies are appropriately matched to the underlying disease, this test increases diagnostic accuracy, assists in choosing the most efficient treatment modalities, and optimizes patient care.
PRECAUTIONS
To get ready for an Immunohistochemistry (IHC) Epithelial Membrane Antigen (EMA) test, talk to your doctor about the importance of the test, your medications, allergies, attire, personal hygiene, fasting requirements, and sample collection. You should also follow the instructions and bring the required identification, insurance information, and pertinent documents. In order to get personalized advice, it's important to interact with your provider. Any drugs, dietary supplements, or allergies that might impact the test findings should be disclosed to your healthcare professional. Maintaining excellent hygiene and wearing comfortable attire will help to reduce contamination during sample collection. Before the treatment, discuss any worries or inquiries you may have with your healthcare professional.