Test Preparation : No special preparation required

Sample : Paraffin Blocks/Tissue in buffered formalin

Methodlogy : IHC

Description :

WHAT IS IT?

The Pancytokeratin Immunohistochemistry (IHC) test is a critical diagnostic technique used in pathology to detect and characterize several kinds of epithelial cells in tissue samples. The cytoskeleton of epithelial cells is made up of pancytokeratins, a protein group. The IHC-Pancytokeratin test employs antibodies to target a wide range of cytokeratins, resulting in a visible stain that pathologists may use to examine the distribution of cytokeratin-positive cells. This test is very beneficial in identifying malignancies of the breast, lung, and gastrointestinal system, where epithelial cells play an important role.

WHY?

The Pancytokeratin Immunohistochemistry (IHC) test is a critical diagnostic technique in pathology that focuses on the detection and characterisation of epithelial cells inside tissue samples. It employs antibodies that target a wide range of cytokeratins, which are proteins that constitute the cytoskeleton of epithelial cells. This test results in a visible stain, which pathologists can use to examine the distribution of cytokeratin-positive cells in tissue. The IHC-Pancytokeratin test is particularly beneficial in identifying malignancies of the breast, lungs, and gastrointestinal system. It gives specific information regarding the existence and distribution of epithelial cells, allowing for more accurate cancer diagnosis and helping healthcare providers in making educated decisions.

PRECAUTION 

Patients must contact with healthcare practitioners and submit information about their medical history, medicines, and existing health issues in order to prepare for an Immunohistochemistry (IHC) Pancytokeratin test. Before the test, there are normally no food or activity limitations, however wearing comfortable attire is recommended. For safe sample management, patients should tell laboratory professionals of any bleeding problems or blood-thinning drugs. It is also critical to follow particular recommendations from healthcare practitioners or laboratories, such as quitting certain drugs or fasting restrictions. This proactive approach improves the dependability of test results, allowing for more accurate diagnosis and the creation of treatment methods tailored to the patient's individual condition.