Test Preparation : No special preparation required

Sample : Paraffin Blocks/Tissue in buffered formalin

Methodlogy : IHC

Description :

WHAT IS IT?

A specific laboratory procedure called immunohistochemistry (IHC) thyroglobulin testing is used to identify and pinpoint the presence of thyroglobulin in tissue samples, particularly those taken from the thyroid gland. A key ingredient in the creation of thyroid hormones is the protein thyroglobulin, which is synthesized by the thyroid gland. Application of certain antibodies that bind to thyroglobulin molecules present in the tissue sections is required for the IHC Thyroglobulin test. The test enables thyroglobulin to be seen under a microscope by using a colorimetric or fluorescent labeling technique. This method is frequently used in thyroid pathology to assist in the diagnosis of conditions connected to the thyroid, including thyroid cancer. Pathologists can identify thyroid tissue in tissue samples, gauge the severity of the condition, and keep track of how well various therapies, including thyroid surgery or radioactive iodine therapy, are working by looking for thyroglobulin. In the setting of thyroid illnesses, the IHC Thyroglobulin test is a useful tool for assisting clinical judgment and offering crucial information for patient therapy.
 
WHY?

A crucial tool for identifying, treating, and keeping track of thyroid-related disorders, including thyroid cancer, is the thyroglobulin test. The thyroid gland makes the protein thyroglobulin, which is used in the manufacture of thyroid hormones. It aids in the early detection of cancer recurrence following thyroidectomy, enabling prompt management. As thyroid cancer cells that have expanded outside of the thyroid gland can absorb radioactive iodine, the test is also utilized in combination with radioactive iodine therapy. The reduction in thyroglobulin levels following treatment shows that the therapy was effective. The test helps with continuing monitoring of patients who have received therapy by identifying probable illness progression or recurrence and enabling quick medical action. Overall, the thyroglobulin test offers critical data that doctors must consider while managing and treating thyroid cancer, assuring the best results for patients.

PRECAUTIONS

It is crucial to discuss any drugs you are taking, including thyroid hormones and any other pertinent ones, with your healthcare practitioner in order to get ready for an Immunohistochemistry (IHC) Thyroglobulin test. Although not often necessary for the exam, if fasting is indicated, abide by their recommendations. Thyroglobulin levels and thyroid function can be impacted by avoiding iodine-rich foods, supplements, and drugs. If the test is a component of a larger medical procedure, dress comfortably and abide by all medical directions. Please let the medical staff know if you have any allergies, illnesses, or procedure-related worries. Stress and anxiety can be lessened with the aid of relaxation methods and hobbies. In general, it's advised to drink enough water, but if fasting is called for, stick to particular rules.